MyBioSource.com's Cofilin 1 antibody is a Rabbit Polyclonal antibody. This antibody has been shown to work in applications such as: Immunohistochemistry. The Cofilin 1 antibody was generated using CFL, Cfl1, Cofilin, and Cofilin 1 as the antigen and it reacts with Human, Mouse, Rat, and Porcine.
Description
Rabbit polyclonal Cofilin 1 antibody
Actin-binding proteins regulate assembly and disassembly of actin filaments. Cofilin, a member of the ADF/cofilin family is actually a protein with 70% sequence homology to ADF, making it part of the ADF/cofilin family of small ADP-binding proteins. The protein binds to actin monomers and filaments, G actin and F actin, respectively. Cofilin causes depolymerization at the minus end of filaments, thereby preventing their reassembly. The protein is known to sever actin filaments by creating more positive ends on filament fragments